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WESTON (CBSMiami) –  It’s a heartbreaking loss for the families of four people killed in a wrong way crash Tuesday night in West Broward.

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The family is with the lone survivor who is hospitalized in serious condition.

The accident happened in the northbound lanes of U.S. 27 just north of I-75 around 9:30 p.m. Tuesday.

The Florida Highway Patrol said 27-year old Nathan Wine, of Delray Beach, was heading south in the northbound lanes when he crashed his Volvo into a Toyota Sequoia driven by 67-year old Hermis Ruiz of Clewiston. Two brothers and their wives were in the SUV, according to the men’s relatives.

Wine and Ruiz were both killed as were Ruiz’s wife, 62-year old Daisy Zayas of Clewiston, and his brother’s wife, 63-year old Ines Zayas Pena from Havana, Cuba.

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The sole survivor of the crash was Ruiz’s brother 69-year old Minerio Ruiz Torres from Havana. He was airlifted to Broward Health North in serious condition, according to FHP spokesman Sgt. Mark Wysocky.

Traffic homicide detectives are looking into whether or not Wine was impaired at the time of the crash.

His family says has been in Delray Beach for about six months. Wine grew up in Indiana.

Wine’s father said he had just been to a family reunion and that his son was an accomplished golfer who worked in petroleum sales.

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Meantime troopers are trying to figure out how he ended up driving the wrong way.