KEY WEST (CBSMiami) – Endurance swimmer Diana Nyad is ready to make one final attempt to swim from Cuba to the Florida Keys.

Nyad has tried to make the swim multiple times in the past. She tried twice in 2011 and one more time in 2012, but was done in each time by either the box jellyfish or poor weather conditions.

READ MORE: Israelis In South Florida Monitoring Violence In Home Country, Want It To Stop

She plans to leave for Cuba on Saturday and if conditions permit, give it one last go.

READ MORE: Woman Who Snuck Into American Sr. High Posing As Student To Promote Instagram Account Bonds Out

Nyad will wear a silicone mask to try to protect her face from the jellyfish, but she said it’s “cumbersome” and “hard to breathe” in. However, she said the tentacles of the jellyfish can’t penetrate the mask.

MORE NEWS: Panic Buying Over Fuel Pipeline Shut Down Has Led To Long Lines At Some South Florida Gas Stations

Thirty-five people will be along for the ride with Nyad hoping she can finally finish her extreme dream.